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Updated: Jul 27, 2025

Three-Dimensional Shape Modeling and Analysis of Brain Structures
Published on: November 14, 2019
An open-source solution for shape modeling and analysis of objects of challenging topologies
Jared Vicory1, David Allemang1, Dzenan Zukic1
1Kitware Inc, Carrboro NC 27510, USA.
Abstract:
Shape analysis is an important and powerful tool in a wide variety of medical applications. Many shape analysis techniques require shape representations which are in correspondence. Unfortunately, popular techniques for generating shape representations do not handle objects with complex geometry or topology well, and those that do are not typically readily available for non-expert users. We describe a method for generating correspondences across a population of objects using a given template. We also describe its implementation and distribution via SlicerSALT, an open-source platform for making powerful shape analysis techniques more widely available and usable. Finally, we show results of this implementation on mouse femur data.
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