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Updated: Jul 27, 2025

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Mollaret's Syndrome: A Case Report.

Vivien M Edi1, Prasad Rao1, Joanna O Igo2

  • 1Internal Medicine, Wellstar Kennestone Hospital, Marietta, USA.

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|June 7, 2023
PubMed
Summary

Benign recurrent aseptic meningitis involves repeated, self-resolving episodes of inflammation around the brain. This case highlights a patient experiencing their seventh such episode, underscoring the condition's recurring nature.

Keywords:
mollaret's lymphocytic meningitismollaret's meningitismollaret's syndromerare diseaseviral meningitis

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Area of Science:

  • Neurology
  • Infectious Diseases

Background:

  • Benign recurrent aseptic meningitis is a rare condition.
  • Characterized by recurrent, self-limited episodes of aseptic meningitis with meningeal irritation, fever, and mononuclear pleocytosis.

Observation:

  • Diagnosis requires exclusion of other causes of lymphocytic meningitis.
  • Episodes typically resolve within 2–7 days with no lasting neurological deficits.

Findings:

  • Aseptic meningitis is often viral; Mollaret's meningitis is associated with herpes simplex virus 2 (HSV-2).
  • The utility of prophylactic medication remains uncertain.

Implications:

  • This case report details a patient experiencing their seventh episode of aseptic meningitis.
  • Further research is needed to clarify the role of prophylactic treatments for recurrent aseptic meningitis.