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Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

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Collision Tumor of the Appendix.

Álvaro Morillo Cox¹, Tatiana Fernandez Trokhimtchouk¹, Luis F Flores¹

¹General Surgery, Universidad Internacional del Ecuador/Axxis Hospital, Quito, ECU.

|June 7, 2023

Summary

A rare case of concurrent appendiceal neuroendocrine tumor (NET) and mucinous neoplasm in a young female highlights the diagnostic challenge of acute abdominal pain. Early detection via laparoscopy is crucial for effective management and improved patient outcomes.

Keywords:

acute abdomen appendiceal tumor appendicitis collision tumour mucinous neoplasm neuroendocrine tumor

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Area of Science:

Gastroenterology
Surgical Pathology
Oncology

Background:

Appendiceal tumors are uncommon, often presenting with non-specific symptoms mimicking acute appendicitis.
Differentiating neoplastic appendiceal conditions from simple inflammation can be diagnostically challenging, particularly in young patients.

Observation:

A 20-year-old female presented with acute abdominal pain, nausea, and vomiting, with initial investigations suggesting inflammation but no clear pathology on imaging.
Diagnostic laparoscopy revealed a thickened, inflamed, and multicystic appendix.

Findings:

Histopathological examination confirmed a rare co-occurrence of a grade 1 mixed well-differentiated neuroendocrine tumor (NET) and a high-grade mucinous neoplasm within the appendix.
Cytology was positive for malignancy, indicating the presence of neoplastic cells.

Implications:

This case underscores the importance of including appendiceal neoplasms in the differential diagnosis for acute abdominal pain, irrespective of patient age.
Laparoscopy proves valuable for diagnosing obscure appendiceal pathologies, and early detection of these rare tumors is vital for optimal patient management and prognosis.