Related Experiment Video
Updated: Jul 28, 2026
Comet Assay as an Indirect Measure of Systemic Oxidative Stress
Published on: May 22, 2015
Oxidative stress-related biomarkers in oral squamous cell carcinoma patients: a systematic review and meta-analysis
Qun Zhou1, Fangfei Ye2, Yin Zhou3
1Department of Stomatology, Shaoxing Maternity & Child Health Care Hospital, Shaoxing, Zhejiang, 312000, China.
Abstract:
Aim: This meta-analysis was conducted to evaluate the serum and salivary levels of oxidative stress-related biomarkers in oral squamous cell carcinoma (OSCC) patients compared with controls. Methods: A search of relevant articles that were published between 1 January 2000 and 20 March 2022, was conducted on three electronic databases (Embase, PubMed and Cochrane Library). Results: A total of 15 articles were included in the meta-analysis. The levels of malondialdehyde (MDA), superoxide dismutase (SOD), reduced glutathione (GSH), glutathione peroxidase (GPx) in serum and MDA and GSH in saliva were significantly changed in the OSCC group compared with healthy controls. Conclusion: This study suggests that some oxidative stress biomarkers may be potential biomarkers in early OSCC diagnosis.
More Related Videos
09:33Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors
Published on: February 7, 2018
09:31Analyzing Oxidative Stress in Murine Intestinal Organoids using Reactive Oxygen Species-Sensitive Fluorogenic Probe
Published on: September 17, 2021
Related Concept Videos
01:46Electron Transport Chain: Complex I and II
ROS generation is regulated and maintained at moderate levels necessary...
02:49Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...