Existential depression: A meaningful diagnostic entity?

To examine the construct of existential depression and whether it represents a distinct diagnostic entity.

Descriptive psychopathology and phenomenology are used to define the characteristics of existential depression and for comparison with other presentations of low mood.

Existential depression can be differentiated from other forms of depression by careful appraisal of symptomatology. Drawing attention to this, and likewise other distinguishable yet under-recognised forms of depression, may help stimulate interest in further research on the classification of mood disorders with the prospect of greater diagnostic specificity and more precise treatment matching.

Existential depression is a clinically discernible diagnostic entity.