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Updated: Jul 27, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
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A Signed Subgraph Encoding Approach via Linear Optimization for Link Sign Prediction.

Zhihong Fang, Shaolin Tan, Yaonan Wang

    IEEE Transactions on Neural Networks and Learning Systems
    |June 8, 2023
    PubMed
    Summary
    This summary is machine-generated.

    We introduce a new method, subgraph encoding via linear optimization (SELO), for link sign prediction in signed networks. SELO outperforms current state-of-the-art models, demonstrating superior performance in predicting link signs.

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    Area of Science:

    • Graph Neural Networks
    • Network Science
    • Machine Learning

    Background:

    • Signed networks represent relationships with positive or negative signs.
    • Link sign prediction is crucial for understanding network structures.
    • Current methods like signed directed graph neural networks (SDGNNs) show strong performance.

    Purpose of the Study:

    • To propose a novel architecture for link sign prediction in signed directed networks.
    • To introduce the subgraph encoding via linear optimization (SELO) model.
    • To evaluate SELO's performance against state-of-the-art methods.

    Main Methods:

    • Developed a subgraph encoding approach to learn edge embeddings.
    • Utilized a linear optimization (LO) method to embed subgraphs into likelihood matrices.
    • Conducted experiments on five real-world signed networks.

    Main Results:

    • SELO achieved leading prediction performances compared to SDGNN.
    • The model outperformed existing feature-based and embedding-based methods.
    • Consistent improvements were observed across all five networks and four evaluation metrics (AUC, F1, micro-F1, macro-F1).

    Conclusions:

    • SELO offers a significant advancement in link sign prediction for signed directed networks.
    • The subgraph encoding via linear optimization approach is effective for learning edge embeddings.
    • The proposed model demonstrates robust and superior performance across diverse real-world datasets.