Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cell Specific Gene Expression01:58

Cell Specific Gene Expression

4.7K
4.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanisms underlying tolerance of severe hypoxia in sulfide spring fish.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology·2026
Same author

Tissue-Specific Plasticity of DNA Methylation Across Intertidal Microhabitats in Juvenile Mussels (Mytilus californianus).

Molecular ecology·2026
Same author

Evolution of genome-wide barriers to gene flow during complex speciation in rattlesnakes.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Zoonotic and Anthroponotic Plasmodium spp. Circulation between Wild Primates and Indigenous Community, Peruvian Amazon, 2007-2020.

Emerging infectious diseases·2026
Same author

Correction: The effects of carnivory and herbivory on the energy balance of Arctic grizzly bears.

Oecologia·2026
Same author

Rete ridges form via evolutionarily distinct mechanisms in mammalian skin.

Nature·2026

Related Experiment Video

Updated: Jul 27, 2025

Isolating Brown Adipocytes from Murine Interscapular Brown Adipose Tissue for Gene and Protein Expression Analysis
07:07

Isolating Brown Adipocytes from Murine Interscapular Brown Adipose Tissue for Gene and Protein Expression Analysis

Published on: March 12, 2021

5.8K

A multi-tissue gene expression dataset for hibernating brown bears.

Blair W Perry1, Michael W Saxton1, Heiko T Jansen2

  • 1School of Biological Sciences, Washington State University, Pullman, WA, 99164, USA.

BMC Genomic Data
|June 8, 2023
PubMed
Summary
This summary is machine-generated.

Researchers generated a unique gene expression dataset from hibernating brown bear tissues. This resource aids understanding of hibernation physiology and may offer insights for human disease treatment.

Keywords:
Brown bearsGene expressionHibernationTranscriptomics

More Related Videos

Author Spotlight: Optimizing Supraclavicular Brown Adipose Tissue Extraction for Genetic Analysis
06:50

Author Spotlight: Optimizing Supraclavicular Brown Adipose Tissue Extraction for Genetic Analysis

Published on: March 29, 2024

2.1K
Isolation of Adipose Tissue Nuclei for Single-Cell Genomic Applications
07:03

Isolation of Adipose Tissue Nuclei for Single-Cell Genomic Applications

Published on: June 12, 2020

10.0K

Related Experiment Videos

Last Updated: Jul 27, 2025

Isolating Brown Adipocytes from Murine Interscapular Brown Adipose Tissue for Gene and Protein Expression Analysis
07:07

Isolating Brown Adipocytes from Murine Interscapular Brown Adipose Tissue for Gene and Protein Expression Analysis

Published on: March 12, 2021

5.8K
Author Spotlight: Optimizing Supraclavicular Brown Adipose Tissue Extraction for Genetic Analysis
06:50

Author Spotlight: Optimizing Supraclavicular Brown Adipose Tissue Extraction for Genetic Analysis

Published on: March 29, 2024

2.1K
Isolation of Adipose Tissue Nuclei for Single-Cell Genomic Applications
07:03

Isolation of Adipose Tissue Nuclei for Single-Cell Genomic Applications

Published on: June 12, 2020

10.0K

Area of Science:

  • Comparative genomics
  • Physiological adaptations
  • Mammalian biology

Background:

  • Complex physiological adaptations require molecular coordination across tissues.
  • Transcriptomic resources are crucial for understanding the genomic basis of phenotypes in non-traditional model organisms.
  • Brown bears (Ursus arctos) exhibit unique phenotypes related to hibernation.

Purpose of the Study:

  • To establish a novel gene expression dataset from multiple tissues of hibernating brown bears.
  • To provide a foundation for investigating the genomic underpinnings of hibernation.
  • To compare bear hibernation physiology with traditional model organisms and explore translational potential for human disease.

Main Methods:

  • Collection of 26 samples from 13 distinct tissues of two hibernating brown bears.
  • Opportunistic sampling yielding a unique and valuable dataset.
  • Integration with previously published datasets for comprehensive analysis.

Main Results:

  • Generation of a one-of-a-kind gene expression dataset from hibernating brown bears.
  • The dataset comprises samples from multiple tissues, offering a detailed molecular snapshot.
  • This resource is valuable for studying the physiology of hibernation.

Conclusions:

  • The presented dataset is a significant transcriptomic resource for brown bear research.
  • It facilitates detailed investigation into the molecular mechanisms of hibernation.
  • This work may offer insights applicable to treating human diseases.