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Updated: Jul 27, 2025
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A 3D Organotypic Melanoma Spheroid Skin Model
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Pigmented Epidermotropic Breast Carcinoma: A Diagnostic Pitfall Mimicking Melanoma A Case Report and Literature
Ines Rolim1,2, Margarida Rafael3, Alistair Robson2,4
1Anatomic Pathology, Fundação Champalimaud, Lisboa, Portugal.
International Journal of Surgical Pathology
|June 9, 2023
Abstract:
We report the clinical and pathologic features of a patient with breast carcinoma, who developed clinically visible pigmented skin lesions during the course of the disease. The combination of clinical pigmentation, histological pagetoid epidermal spread, and considerable melanin pigment within tumour cells lead to a misdiagnosis of melanoma. This case provides a striking example of the ability of epidermotropic breast carcinoma to mimic melanoma. A literature review is also reported.
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