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Updated: Jul 27, 2025

Intraductal Delivery to the Rabbit Mammary Gland
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Ductal carcinoma

Nguyen Thu Huong1, Tran-Thi Hue1, Nguyen Duy Hung2

  • 1Department of Radiology, Vinmec Healthcare System, Ha Noi, Vietnam.

Journal of Clinical Imaging Science
|June 9, 2023
PubMed
Summary

This report details a rare case of ductal carcinoma in situ (DCIS) originating in microglandular adenosis (MGA) and atypical microglandular adenosis (AMGA) in a young woman. Early detection and management were key, preventing invasive breast cancer progression.

Keywords:
Atypical microglandular adenosisBreastDuctal carcinoma in situMagnetic resonance imagingMicroglandular adenosisUltrasound

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Area of Science:

  • Oncology
  • Breast Pathology
  • Radiology

Background:

  • Microglandular adenosis (MGA) and atypical microglandular adenosis (AMGA) are rare breast lesions.
  • Carcinoma arising in MGA/AMGA is exceptionally uncommon, with most cases being invasive.
  • Accurate diagnosis relies on imaging modalities like ultrasound and MRI.

Observation:

  • A palpable breast mass was noted in a very young Vietnamese woman.
  • Clinical examination and imaging revealed suspicious lesions categorized as BI-RADS 4a.
  • The patient presented with a 1-month history of the palpable mass.

Findings:

  • Histopathology confirmed ductal carcinoma in situ (DCIS) arising from MGA/AMGA.
  • The diagnosed DCIS was localized within the duct without signs of invasion.
  • This represents a rare instance of non-invasive carcinoma developing in MGA/AMGA.

Implications:

  • Highlights the importance of vigilant diagnosis of MGA/AMGA, even in young patients.
  • Emphasizes the potential for DCIS development within these rare breast lesions.
  • Early detection and management of localized DCIS in MGA/AMGA can prevent invasive breast cancer.