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Related Concept Videos

Precipitation Processes01:12

Precipitation Processes

495
The experimental conditions in a gravimetric analysis should be optimized to maximize the particle size and purity of the obtained precipitate. Ideally, the concentration of the precipitating reagent should be low with effective stirring to maintain low relative supersaturation for the growth of large crystals. In homogeneous precipitation, the precipitant is slowly generated by a chemical reaction in the solution to avoid local reagent excesses. For example, urea decomposes gradually to...
495

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Related Experiment Video

Updated: Jul 27, 2025

Frugal Imaging Technique of Capillary Flow Through Three-Dimensional Polymeric Printing Powders
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A concise summary of powder processing methodologies for flow enhancement.

Devanshi S Shah1, Kailas K Moravkar2,3, Durgesh K Jha1,4

  • 1Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai, India.

Heliyon
|June 9, 2023
PubMed
Summary
This summary is machine-generated.

Understanding powder properties is crucial for efficient manufacturing. This review details techniques to improve powder flowability, enhancing plant output and minimizing production issues.

Keywords:
Flow testersMixing processPhysicochemical propertiesPowder flowabilityPowder morphology

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Area of Science:

  • Pharmaceutical Sciences
  • Chemical Engineering
  • Materials Science

Background:

  • Powder properties are critical for solid dosage form manufacturing, with historical significance dating back to the 19th century.
  • Poor powder flow can lead to manufacturing process disruptions and equipment malfunction.
  • Effective powder flow is essential for consistent production and product quality.

Purpose of the Study:

  • To summarize common powder flow problems encountered in manufacturing.
  • To present various techniques for improving powder flowability, particularly for cohesive powders.
  • To enhance understanding of powder mechanics for increased plant efficiency.

Main Methods:

  • Review of compendial and non-compendial methods for assessing powder physical properties.
  • Analysis of powder behavior under stress and shear during processing.
  • Focus on practical approaches to rectify and improve powder flow characteristics.

Main Results:

  • Identification of key challenges associated with poor powder flow.
  • Enlistment of diverse techniques to enhance powder flow properties.
  • Demonstration of how improved flowability leads to increased manufacturing efficiency.

Conclusions:

  • Addressing powder flow issues is vital for optimizing pharmaceutical and chemical manufacturing.
  • Implementing appropriate powder flow enhancement techniques can significantly boost plant output.
  • This review provides a comprehensive guide to managing and improving cohesive powder flow.