Endovascular management of intracranial aneurysms at Chris Hani Baragwanath Academic Hospital

Herchel Clarke1, Trevor Nefale1, Victor Mngomezulu1

  • 1Department of Radiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

PubMed

Insights

Endovascular treatment for intracranial aneurysms is effective, with rupture occurring at smaller sizes. This study highlights key patient and aneurysm characteristics in a resource-limited setting.

Area of Science:

  • Neurosurgery
  • Interventional Neuroradiology
  • Vascular Neurology

Background:

  • Intracranial aneurysms pose a significant global mortality risk.
  • Endovascular management is a preferred treatment for select patients.
  • Patient demographics and aneurysm characteristics vary across populations.

Purpose of the Study:

  • To investigate the profile of patients with intracranial aneurysms undergoing endovascular treatment.
  • To analyze patient demographics, risk factors, indications, and aneurysm characteristics.
  • To assess intra-operative complications in a specific healthcare setting.

Main Methods:

  • Retrospective study over three years (January 2018 - January 2021).
  • Inclusion of all adult patients undergoing endovascular management.
  • Statistical analysis using the Chi-square test for categorical variables.

Main Results:

  • 77 patients included; mean age 47 ± 11.6 years; male-to-female ratio 1:1.8.
  • Hypertension was the most common risk factor (27%).
  • Ruptured aneurysms, small neck size (<4mm), and internal cerebral artery (ICA) locations showed statistical significance (p=0.020, p=0.010, p=0.001 respectively).

Conclusions:

  • Findings align with known female preponderance and anterior circulation aneurysm prevalence.
  • Endovascular management demonstrated a low complication rate.
  • Intracranial aneurysms were observed to rupture at smaller dimensions.
Abstract

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