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The radiologic progression of ameloblastomas
Lene Merbold1, Chané Smit1, Jason Ker-Fox2
1Department of Oral and Maxillofacial Pathology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
SA Journal of Radiology
|June 9, 2023
Summary
Delayed treatment for ameloblastoma (AB) leads to significant tumor growth and changes in lesion characteristics. Early intervention is crucial for better management and outcomes in patients with this aggressive jaw tumor.
Area of Science:
- Oral and Maxillofacial Surgery
- Oncology
- Radiology
Background:
- Ameloblastoma (AB) diagnosis in developing countries often faces treatment delays due to patient and healthcare system factors.
- Delayed treatment can lead to significant progression of ameloblastoma, impacting patient prognosis.
Purpose of the Study:
- To analyze the radiologic progression of ameloblastoma with delayed treatment.
- To highlight the detrimental effects of delayed treatment on ameloblastoma growth and characteristics.
Main Methods:
- Retrospective review of 57 histopathologically confirmed ameloblastoma cases over 10 years.
- Analysis of initial and follow-up panoramic radiographs and cone-beam computed tomography (CBCT) imaging.
- Evaluation of changes in lesion borders, locularity, surrounding structures, and size.
Main Results:
- Delayed treatment resulted in a three-fold average increase in ameloblastoma size.
- Lesions showed increased poorly-demarcated borders, transformation from unilocular to multilocular, cortical thinning, and destruction.
- A statistically significant relationship was found between lesion duration and size.
Conclusions:
- Ameloblastomas with delayed treatment exhibit aggressive growth, complicating management.
- Timely management of ameloblastoma is essential due to its aggressive nature and growth potential.
