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A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage
Published on: July 28, 2018
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Automated cerebral hemorrhage volume calculation and stability detection using automated software
Anirudh Sreekrishnan1, Chitra Venkatasubramanian1, Jeremy J Heit1
1Stanford University School of Medicine.
Research Square
|June 9, 2023
Summary
Automated software accurately measures intracerebral hemorrhage (ICH) volume and detects expansion on repeat imaging, offering a rapid alternative to manual analysis for clinical management.
Area of Science:
- Neurology
- Medical Imaging
- Radiology
Background:
- Accurate measurement of intracerebral hemorrhage (ICH) volume is crucial for patient management and evaluating disease progression.
- Manual volumetric analysis of ICH is time-consuming and impractical in busy clinical settings.
Approach:
- This study evaluated the performance of automated Rapid Hyperdensity software for ICH volume measurement.
- A comparison was made between manual measurements by a neuroimaging expert and automated software using data from two clinical trials.
Key Points:
- Automated software demonstrated high correlation with manual measurements for baseline ICH volume (r = 0.994).
- The software accurately detected ICH volume changes on repeat imaging, with high correlation of absolute differences (r = 0.941).
- Automated detection of ICH expansion achieved 94.12% sensitivity and 97.27% specificity.
Conclusions:
- Automated Rapid Hyperdensity software provides a reliable and efficient method for measuring ICH volume.
- The software accurately identifies ICH expansion on serial imaging, supporting its use in clinical practice.
