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Primary ovarian lymphoma: A case report
Charlotte Gerrity1, Alyssa Mercadel2, Abrar Alghamdi3
1Department of Obstetrics and Gynecology, University of Miami, Miami, FL, United States.
Gynecologic Oncology Reports
|June 9, 2023
Summary
Ovarian involvement by Non-Hodgkin Lymphoma (NHL) is uncommon at diagnosis. This case highlights a rare presentation of Diffuse Large B-Cell Lymphoma mimicking ovarian cancer in a young woman.
Area of Science:
- Oncology
- Gynecologic Oncology
- Hematology
Background:
- Non-Hodgkin Lymphoma (NHL) rarely presents as an adnexal mass.
- Ovarian involvement in NHL is more commonly found incidentally at autopsy.
Observation:
- A 20-year-old female presented with a large adnexal mass and elevated tumor markers (B-HCG, CA-125, LDH).
- Initial intraoperative frozen section suggested a dysgerminoma.
Findings:
- Final pathology revealed Ann Arbor stage IVE Diffuse Large B-Cell Lymphoma, germinal center subtype.
- This represents a rare primary presentation of NHL in the ovary.
Implications:
- This case underscores the importance of considering lymphoma in the differential diagnosis of ovarian masses, even in young patients.
- Accurate diagnosis is crucial for appropriate treatment, such as chemotherapy (e.g., R-CHOP).
