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Shalini A Mohan¹, Zharif Sufyaan¹

¹Department of Internal Medicine, Ampang Hospital, Ampang, Selangor, Malaysia.

Case Reports in Infectious Diseases

|June 9, 2023

Summary

This summary is machine-generated.

Listeria monocytogenes caused rare cerebritis and infective endocarditis in a patient. Prompt recognition and treatment are crucial for these deadly conditions.

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Area of Science:

Infectious Diseases
Neurology
Cardiology

Background:

Listeria monocytogenes infections, particularly cerebritis and infective endocarditis, are exceptionally uncommon.
Early diagnosis and intervention are critical for managing severe Listeria monocytogenes infections.

Observation:

A 56-year-old male presented with neurological symptoms including speech slurring and weakness.
Initial diagnosis was multifocal chronic cerebral infarcts, but blood cultures later identified Listeria monocytogenes.

Findings:

Contrast-enhanced computed tomography (CECT) confirmed right frontal cerebritis, leading to a diagnosis of neurolisteriosis.
Transthoracic echocardiogram revealed a large 2.01 cm vegetation on the mitral valve, indicating infective endocarditis.
Despite treatment with intravenous benzyl penicillin, the patient developed respiratory failure and ultimately succumbed to the illness.

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Implications:

This case highlights the rare but severe presentation of Listeria monocytogenes causing both cerebritis and infective endocarditis.
Clinicians must maintain a high index of suspicion for Listeria monocytogenes in patients with neurological and cardiac symptoms.
Timely and appropriate treatment is essential for improving outcomes in these life-threatening infections.