The acromegaly treatment satisfaction questionnaire (Acro-TSQ): turkish adaptation, validity, and reliability study

Area of Science:

• Endocrinology
• Patient-Reported Outcomes
• Psychometrics

Background:

• Patient-reported outcomes (PROs) are crucial for evaluating patient perceptions and informing treatment strategies.
• Acromegaly treatment satisfaction is a key aspect of managing this rare endocrine disorder.

Purpose of the Study:

• To adapt and validate the Acromegaly Treatment Satisfaction Questionnaire (Acro-TSQ) for use in the Turkish-speaking population.
• To assess the psychometric properties of the Turkish version of the Acro-TSQ.

Main Methods:

• The Acro-TSQ underwent translation and back-translation.
• 136 patients with acromegaly receiving somatostatin analogue therapy completed the questionnaire via face-to-face interviews.
• Internal consistency, content validity, construct validity, and reliability were evaluated.

Main Results:

• The Turkish Acro-TSQ demonstrated a six-factor structure, explaining 77.2% of the total variance.
• High internal consistency was confirmed with a Cronbach's alpha of 0.870.
• Exploratory and Confirmatory Factor Analyses indicated acceptable fit indices and item loadings, with minor variations from the original scale.

Conclusions:

• The Turkish version of the Acro-TSQ is a valid and reliable patient-reported outcome measure.
• This tool is suitable for assessing treatment satisfaction in Turkish patients with acromegaly.