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Updated: Jul 27, 2025
07:49
Creating and Applying a Reference to Facilitate the Discussion and Classification of Proteins in a Diverse Group
Published on: August 16, 2017
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Insight into crustacean cathepsins: Structure-evolutionary relationships and functional roles in physiological
Isma Gul1, Muhammad Nadeem Abbas1, Saima Kausar1
1Cancer Center, Medical Research Institute, Southwest University, Chongqing, 400716, China; State Key Laboratory of Resource Insects, Southwest University, Chongqing, 400716, China.
Fish & Shellfish Immunology
|June 9, 2023
Summary
Cathepsins are conserved proteins vital for crustacean reproduction, growth, and immunity. Understanding these proteases offers new strategies for aquaculture management.
Area of Science:
- Biochemistry
- Molecular Biology
- Aquaculture Science
Background:
- Cathepsins are highly conserved proteins found in prokaryotic and eukaryotic organisms.
- They function extracellularly, on plasma membranes, and within various cellular compartments.
- Sequence variations lead to diverse structures and functions among cathepsin groups.
Purpose of the Study:
- To review the biological roles of cathepsins in crustaceans.
- To emphasize their functions in reproduction, growth, development, and immune responses.
- To explore the potential of cathepsins as targets for aquaculture management.
Main Methods:
- Literature review focusing on crustacean cathepsin research.
- Analysis of existing data on cathepsin expression and function.
- Synthesis of information regarding cathepsin bioactivity and physiological roles.
Main Results:
- Cathepsins are ubiquitously expressed proteases in crustaceans.
- They play central regulatory roles in crustacean reproduction, growth, and immunity.
- Crustacean cathepsins exhibit diverse bioactivities.
Conclusions:
- Cathepsins are critical for key physiological processes in crustaceans.
- Their involvement in reproduction, growth, and immunity highlights their importance.
- Cathepsins represent promising targets for novel aquaculture management strategies.
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