Measurement of Stroke Volume With Echocardiography Compared to Gold Standard Cardiac Magnetic Resonance Imaging: An

Brian Cowie1, Leah Wright2, Ben Costello2

  • 1Department of Anaesthesia, St. Vincent's Hospital, Melbourne, Australia; Sports Cardiology, Baker Heart and Diabetes Institute, Melbourne, Australia; Department of Critical Care, University of Melbourne, Melbourne, Australia.

Insights

Transthoracic echocardiography (TTE) methods for measuring left ventricular (LV) stroke volume were compared to cardiac magnetic resonance imaging (CMR). LVOT Doppler with 3D LVOT area showed the closest agreement with CMR.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Echocardiography

Background:

  • Left ventricular (LV) stroke volume assessment is crucial for cardiovascular evaluation.
  • Transthoracic echocardiography (TTE) offers various techniques for LV stroke volume measurement.
  • Comparison with cardiac magnetic resonance imaging (CMR), the gold standard, is essential for validating TTE methods.

Purpose of the Study:

  • To compare the accuracy of different TTE techniques for assessing LV stroke volume against CMR.
  • To determine which TTE method provides the closest estimation of LV stroke volume to CMR.

Main Methods:

  • An observational study involving 187 healthy volunteers.
  • LV stroke volume was measured using four TTE techniques: 2D/3D LV outflow tract (LVOT) Doppler and 2D/3D volumetric methods.
  • Measurements were compared with those obtained via gold standard CMR.

Main Results:

  • All TTE techniques underestimated LV stroke volume compared to CMR (p < 0.001).
  • LVOT Doppler with a 3D LVOT area demonstrated the least bias (6.35%) compared to CMR.
  • Increasing bias was observed with 3D volumetric (13.4%), 2D LVOT Doppler (15.1%), and 2D volumetric (18.3%) methods.

Conclusions:

  • LVOT Doppler using 3D measurement of the LVOT area is the most accurate TTE method for estimating LV stroke volume when compared to CMR.
  • This finding suggests that 3D echocardiography may improve the precision of stroke volume assessment.
Abstract

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