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Updated: Oct 23, 2026

Investigating Aortic Valve Calcification via Isolation and Culture of T Lymphocytes using Feeder Cells from Irradiated Buffy Coat
Published on: February 4, 2021
Myocardial infarction secondary to calcific embolization: an unusual complication of bioprosthetic valve degeneration
Insights
A degenerated bovine pericardial bioprosthesis caused calcific embolization in the coronary arteries, leading to acute myocardial infarction in a patient. This case highlights a rare complication of aortic valve bioprosthetic devices.
Area of Science:
- Cardiology
- Cardiac Surgery
- Biomaterials Science
Background:
- Degeneration of bioprosthetic heart valves is a known complication.
- Calcific embolization from prosthetic valves is a rare but serious event.
- Ionescu-Shiley bovine pericardial bioprostheses have a history of degeneration.
Abstract:
A patient with coronary artery embolization of calcific material from a degenerated Ionescu-Shiley bovine pericardial bioprosthesis in the aortic position with resultant acute myocardial infarction is described.
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