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Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

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Related Experiment Video

Updated: Jun 28, 2026

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
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A Novel COVID-19 Diagnostic System Using Biosensor Incorporated Artificial Intelligence Technique.

Md Mottahir Alam1, Md Moddassir Alam2, Hidayath Mirza3

  • 1Department of Electrical and Computer Engineering, Faculty of Engineering, King Abdulaziz, Jeddah 21589, Saudi Arabia.

Diagnostics (Basel, Switzerland)
|June 10, 2023
PubMed
Summary
This summary is machine-generated.

A new Shuffle Shepherd Optimization-based Generalized Deep Convolutional Fuzzy Network (SSO-GDCFN) accurately diagnoses COVID-19 states, types, and recovery. This advanced method achieves near-perfect accuracy, offering a significant improvement for disease classification.

Keywords:
COVID-19artificial intelligencebiosensorfeature extractionhyperparameteroptimization

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Area of Science:

  • Medical Informatics
  • Artificial Intelligence in Medicine
  • Infectious Disease Modeling

Background:

  • COVID-19 poses a significant global health threat with high incidence and mortality.
  • Accurate and timely diagnosis of COVID-19 disease state, types, and recovery is crucial for effective patient management and public health strategies.
  • Existing diagnostic methods may have limitations in speed, accuracy, or ability to categorize disease progression.

Purpose of the Study:

  • To introduce and evaluate a novel deep learning model, the Shuffle Shepherd Optimization-based Generalized Deep Convolutional Fuzzy Network (SSO-GDCFN), for COVID-19 diagnosis.
  • To assess the capability of SSO-GDCFN in classifying COVID-19 disease states, types, and recovered categories.
  • To demonstrate the superior performance of SSO-GDCFN compared to traditional diagnostic techniques.

Main Methods:

  • Development of a hybrid deep learning architecture integrating fuzzy logic and convolutional neural networks.
  • Optimization of the network using the Shuffle Shepherd Optimization algorithm.
  • Training and validation of the SSO-GDCFN model on a dataset for COVID-19 diagnosis and classification.

Main Results:

  • The proposed SSO-GDCFN achieved exceptional diagnostic accuracy of 99.99%.
  • Key performance metrics include 99.98% precision, 100% sensitivity/recall, 95% specificity, 0.965% kappa, 0.88% AUC, and Mean Squared Error (MSE) below 0.07%.
  • The model demonstrated rapid processing with results obtained in approximately 25 seconds, outperforming conventional methods in accuracy and minimizing reclassification errors.

Conclusions:

  • The SSO-GDCFN model presents a highly accurate and efficient tool for diagnosing and categorizing COVID-19.
  • This advanced computational approach offers significant potential for improving clinical decision-making in infectious disease management.
  • The study highlights the effectiveness of integrating optimization algorithms with deep fuzzy networks for complex medical diagnostic tasks.