Monoclonal antibodies against Chilo iridescent virus (iridovirus type 6). Brief report

Archives of Virology
|January 1, 1986
PubMed

Mouse hybridomas producing antibodies against proteins of Chilo Iridescent Virus were established by fusions of X 63-Ag 8-653 myeloma cells with spleen cells from balb/c mice immunized with purified disrupted viral particles. Forty monoclonal antibodies to CIV proteins have been characterized. By ELISA, 4 categories of monoclonal antibodies were defined according to their ability to react with some selected viral protein fractions used as antigen. In preliminary studies, the specificity of 2 monoclonal antibodies for some viral polypeptides was determined by immunoblotting.

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