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Updated: Jul 27, 2025

Generation and Coherent Control of Pulsed Quantum Frequency Combs
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Fractional CO

Youn-Jee Chung1, Suhyun Shim1, Sejin Kim1

  • 1Department of Obstetrics and Gynecology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.

Journal of Clinical Medicine
|June 10, 2023
PubMed
Summary
This summary is machine-generated.

Fractional CO2 laser therapy effectively improved genitourinary syndrome of menopause (GSM) symptoms and vaginal health in Korean women. The treatment demonstrated safety and high patient satisfaction, warranting further investigation into long-term effects.

Keywords:
CO2 lasergenitourinary syndrome of menopausemenopausevaginal drynessvulvovaginal atrophy

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Area of Science:

  • Gynecology
  • Dermatology
  • Laser Medicine

Background:

  • Genitourinary syndrome of menopause (GSM) significantly impacts women's quality of life.
  • Conservative treatments for GSM have limitations.
  • Fractional CO2 laser therapy is an emerging option for GSM management.

Purpose of the Study:

  • To evaluate the efficacy and safety of fractional CO2 laser therapy for GSM in Korean women.
  • To assess the impact of laser treatment on GSM symptoms and vaginal health.
  • To determine patient satisfaction with fractional CO2 laser therapy.

Main Methods:

  • Thirty Korean women with GSM received three fractional CO2 laser sessions at 4-week intervals.
  • GSM symptom severity was measured using a visual analog scale (VAS).
  • Vaginal health was objectively assessed using the vaginal health index score (VHIS) and Vaginal Maturation Index (VMI).

Main Results:

  • Significant improvement in GSM symptoms, including vaginal dryness and urgency, was observed after two sessions.
  • All GSM symptoms and VHIS showed significant improvement (p < 0.05) after the complete treatment course.
  • High patient satisfaction (average 4.3/5) was reported, with no major safety concerns.

Conclusions:

  • Fractional CO2 laser therapy is an effective and safe treatment for genitourinary syndrome of menopause in Korean women.
  • The treatment leads to significant improvements in both subjective and objective measures of GSM.
  • Further research is recommended to confirm these findings and evaluate long-term outcomes.