Atherosclerotic and Cardio-Metabolic Diseases: From Molecular Basis to Therapeutic Advances

Eva Kassi1,2, Ioannis Kyrou3,4,5,6,7, Harpal S Randeva3,4

  • 1Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.

Insights

Cardiovascular diseases (CVDs) remain a leading cause of death globally. However, mortality rates are declining due to lifestyle changes, new drugs, and surgical advancements.

Area of Science:

  • Cardiology
  • Public Health
  • Medical Research

Background:

  • Cardiovascular diseases (CVDs) represent a significant global health burden.
  • Despite their prevalence, CVD-related mortality shows a downward trend.

Discussion:

  • Lifestyle modifications are crucial in managing and preventing CVDs.
  • Novel pharmacological therapies offer improved treatment options.
  • Advancements in cardiovascular surgery contribute to better patient outcomes.

Key Insights:

  • Multifaceted interventions, including lifestyle, pharmacology, and surgery, are effective in reducing CVD mortality.
  • The integration of these approaches is key to combating cardiovascular disease burden.

Outlook:

  • Continued research into novel therapies and surgical techniques is essential.
  • Public health initiatives promoting healthy lifestyles remain vital.
  • Future strategies should focus on personalized and integrated CVD management.

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