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Facial Feedback Hypothesis01:24

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Charles Darwin proposed that facial expressions are an evolutionary adaptation for communication. He argued that these expressions are not influenced by culture but are universal across species. For example, a snarling expression with exposed teeth signals a threat in many animals, including humans. Darwin also suggested that displaying an emotion can intensify the feeling. Smiling, for example, could enhance one's sense of happiness. This idea laid the foundation for understanding the role...
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Oral and craniofacial research in the Generation R study: an executive summary.

Agatha W van Meijeren-van Lunteren1,2, Xianjing Liu1,2,3, Francien C H Veenman1,2

  • 1Department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus University Medical Centre, PO Box 2040, 3000 CA, Rotterdam, the Netherlands.

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This study details the Generation R cohort, a Dutch birth cohort, collecting extensive oral and craniofacial data from childhood to adulthood to understand oral disease determinants. This research aims to improve oral health care and promotion strategies.

Keywords:
Cohort studiesDental healthDental public healthEpidemiologyPopulation-based

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Area of Science:

  • Oral Health Research
  • Epidemiology
  • Developmental Biology

Background:

  • Oral conditions are prevalent and chronic, necessitating identification of risk factors for improved public health.
  • Longitudinal birth cohort studies are crucial for understanding oral disease etiology and promoting lifelong oral health.
  • The Generation R study in the Netherlands is a prospective birth cohort designed to investigate health determinants from fetal life onwards.

Purpose of the Study:

  • To provide an overview of the comprehensive oral and craniofacial dataset within the Generation R study.
  • To highlight the potential of this dataset for identifying risk factors and determinants of common oral diseases.
  • To emphasize the importance of early life factors for long-term oral health outcomes.

Main Methods:

  • Oral and craniofacial data collected from participants aged 3 to 17 years within a multidisciplinary birth cohort.
  • Data collection includes questionnaires on oral hygiene, habits, quality of life, and sleep apnea.
  • Direct measurements encompass dental caries, enamel defects, orthodontic needs, dental development, and craniofacial morphology.

Main Results:

  • The Generation R cohort includes 9749 children at birth, with 7405 eligible participants at age 17.
  • The dataset captures diverse oral health information, from hygiene practices to clinical outcomes like caries and enamel defects.
  • Craniofacial characteristics, including 3D facial measurements and mandibular cortical thickness, are comprehensively documented.

Conclusions:

  • Multiple research avenues are being pursued using the Generation R oral and craniofacial data.
  • The study's longitudinal and multidisciplinary nature facilitates in-depth investigation of oral and craniofacial health determinants.
  • This dataset offers valuable insights into the etiology of oral health problems in the general population.