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Updated: Jul 27, 2025

Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach
Published on: June 5, 2010
Intra-abdominal myositis ossificans - a clinically challenging disease: A case report
Gabriele Carbone1, Valentina Andreasi1, Paola De Nardi2
1Department of Gastrointestinal Surgery, IRCCS San Raffaele Hospital, Milan 20132, Italy.
Background:
Myositis ossificans (MO) is an uncommon disorder characterized by heterotopic ossification within soft tissues. Only a few cases of intra-abdominal MO (IMO) have been described in the literature. Histology could be difficult to understand and a wrong diagnosis could lead to an improper cure.
Case Summary:
We herein report the case of IMO in a healthy 69-year-old man. The patient presented with an abdominal mass in the left lower quadrant. A computed tomography scan showed an inhomogeneous mass with multiple calcifications. The patient underwent radical excision of the mass. Histopathological findings were compatible with MO. Five months later the patient showed a recurrence causing hemorrhagic shock due to intractable intralesional bleeding. The patients eventually died within three months since recurrence.
Conclusion:
The case described could be classified as post-traumatic MO that developed close to the previously fractured iliac bone. The subsequent surgical procedure was ineffective and the disease rapidly recurred. The misleading intraoperative diagnosis led to improper surgical treatment with a dramatic evolution.

