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Aortic valve-sparing procedure in the pediatric population
Yves d'Udekem1, Eiri Kisamori1, Shuta Ishigami2
1Division of Cardiovascular Surgery, Children's National Heart Institute, Children's National Hospital, Washington, DC, USA.
Insights
Aortic valve-sparing surgery is feasible in children with aortic root aneurysms, though complex. This pediatric study shows successful outcomes with the David procedure, but highlights the need for surgical expertise.
Area of Science:
- Pediatric Cardiac Surgery
- Aortic Valve Repair
- Aortic Root Aneurysm Management
Background:
- Aortic valve-sparing procedures are standard for adults with aortic root aneurysms.
- Limited data exists on pediatric application of these valve-sparing techniques.
- This study addresses the use of aortic valve-sparing procedures in children.
Purpose of the Study:
- To evaluate the safety and efficacy of aortic valve-sparing procedures in pediatric patients.
- To report outcomes of aortic valve-sparing surgery in a pediatric cohort.
Main Methods:
- Retrospective review of pediatric patients undergoing aortic valve-sparing procedures.
- Data collected from April 2006 to April 2016 at a single institution.
- Analysis of clinical and echocardiographic data.
Main Results:
- Seventeen pediatric patients (median age 15.7 years) underwent the David procedure.
- Common diagnoses included transposition of great arteries, Loeys-Dietz, and Marfan syndromes.
- High rates of preoperative aortic regurgitation (94.1%) were noted. Freedom from reoperation at 10 years was 68.2%.
Conclusions:
- Aortic valve-sparing surgery can be successfully performed in pediatric patients.
- The procedure demands significant surgical skill due to complex valve anatomy.
- Additional leaflet procedures may be necessary for optimal outcomes.
Background:
Aortic valve-sparing procedures have been established as a mainstream treatment option for adult patients with aortic root aneurysms. However, data regarding their use in the pediatric population is limited. This study reports on our experience with aortic valve-sparing procedures in children.
Methods:
A retrospective review was conducted of all patients who underwent an aortic valve-sparing procedure at the Royal Children's Hospital, Melbourne, Australia between April 2006 and April 2016. Clinical and echocardiographic data were analyzed.
Results:
The study included 17 patients, with a median age of 15.7 years and a majority of patients being male (82.4%). The most common diagnosis was transposition of great arteries after arterial switch operation, followed by Loeys-Dietz syndrome and Marfan syndrome. Preoperative echocardiography showed more than moderate aortic regurgitation in 94.1% of the patients. The David procedure was performed in all 17 patients, with no mortality during follow-up. Reoperation was required in 29.4% of patients, and 23.5% required aortic valve replacement. Freedom from reoperation for aortic valve replacement at 1, 5, and 10 years was 93.8%, 93.8% and 68.2% respectively.
Conclusions:
Aortic valve-sparing surgery can be successfully performed in the pediatric population. However, it requires a highly skilled surgeon due to the often dysplastic or distorted nature of these valves and the need for additional procedures on the aortic valve leaflets.
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