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Updated: Jul 27, 2025

Creation of a Rodent Model of Abdominal Aortic Aneurysm by Blocking Adventitial Vasa Vasorum Perfusion
Published on: November 8, 2017
The natural history of aortic root aneurysms
Bulat A Ziganshin1, Nicole Kargin1, Mohammad A Zafar1
1Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT, USA.
Abstract:
The aortic root has a different embryologic origin from all other segments of the human aorta, a feature that likely confers unique susceptibilities, anatomical patterns, and clinical behavior of aneurysm disease in this vital location. In this manuscript, we review the natural history of ascending aortic aneurysm, with a specific focus on the aortic root. The specific central message is that root dilatation is more malignant than ascending dilatation.
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