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Published on: March 24, 2023
Fatty liver and celiac disease: Why worry?
Janaina Luz Narciso-Schiavon1, Leonardo Lucca Schiavon2
1Department of Internal Medicine, Gastroenterology Division, Federal University of Santa Catarina, Florianópolis 88040-900, Santa Catarina, Brazil. janaina.narciso@uol.com.br.
Celiac disease (CD) is an intestinal disorder triggered by gluten. Screening for CD is advised in patients with liver conditions, especially autoimmune disorders and fatty liver disease, due to their frequent association.
Area of Science:
- Gastroenterology and Hepatology
- Immunology
Background:
- Celiac disease (CD) is a chronic inflammatory intestinal disorder.
- Liver involvement is common in CD patients.
- Non-alcoholic fatty liver disease (NAFLD) affects 25% of adults globally.
Purpose of the Study:
- To review the literature on the correlation between fatty liver and celiac disease.
- To identify specific clinical characteristics in patients with both conditions.
Main Methods:
- Literature review of studies investigating fatty liver and celiac disease.
- Analysis of clinical presentations and associations.
Main Results:
- Celiac disease screening is recommended for patients with various liver diseases.
- Specific liver conditions warrant increased suspicion for celiac disease.
- The study highlights the clinical significance of co-occurrence.
Conclusions:
- There is a significant correlation between fatty liver and celiac disease.
- Clinical vigilance for celiac disease is crucial in patients with liver conditions.
- Further research into the shared mechanisms is warranted.
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