[Transformation and ultrastructural changes in erythrocytes during sensitization by serum protein]

Sensibilization of white rats by horse serum protein has led to quantitative and qualitative changes in internal erythrocyte structure. At the same time changes in leucocyte functional activity and immunocomplex circulation took place. Sensibilization has resulted in the rise of echinocyte, poikilocyte and schizocyte blood level. Sensibilization caused activation of spherulation and partial erythrolysis. The processes are induced by the alterations of cellular ultrastructure.