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Reducing oxidative protein folding alleviates senescence by minimizing ER-to-nucleus H2 O2 release

Fang Cheng1,2, Qianzhao Ji2,3, Lu Wang1

  • 1National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.

EMBO Reports
|June 12, 2023
PubMed

Keywords:
human mesenchymal stem cells (hMSCs)hydrogen peroxide (H2O2)oxidative protein foldingprotein disulfide isomerase (PDI)senescence

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