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Photodynamic immunotherapy using ADU-S100-modified nanoparticles to treat triple-negative breast cancer

Tong Ge1, Wenshu Ge2, Ludan Zhang2

  • 1Department of Immunology, Key Laboratory of Immune Microenvironment & Disease of the Educational Ministry of China, Tianjin Key Laboratory of Cellular & Molecular Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, 300070, China.

Nanomedicine (London, England)
|June 12, 2023
PubMed

Keywords:
STING agonistcGAS/STING pathwayimmune checkpoint blockade therapyimmunotherapyphotodynamic therapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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