The changing face of cardiogenic shock: definitions, epidemiology, and severity assessment

Jacob C Jentzer1, David A Baran2

  • 1Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.

Insights

Cardiogenic shock (CS) definitions and severity assessment are evolving. Recent advances in evaluating CS severity may improve patient outcomes by enabling tailored therapies.

Area of Science:

  • Cardiology
  • Critical Care Medicine

Background:

  • Cardiogenic shock (CS) is a critical condition, often stemming from myocardial infarction, with a long-recognized history.
  • Despite decades of recognition, mortality rates for CS have remained largely unchanged.

Approach:

  • This review synthesizes recent advancements in understanding CS, focusing on evolving definitions and epidemiological data.
  • It details contemporary methods for assessing shock severity, including lactate measurement and invasive hemodynamic monitoring.
  • The review examines the Society for Cardiac Angiography and Intervention (SCAI) consensus statement on the Classification of Cardiogenic Shock and its implications.

Key Points:

  • Evolving definitions of CS are discussed, contrasting historical approaches with current concepts.
  • Epidemiological trends of CS are presented.
  • Granular assessment of shock severity, utilizing tools like lactate levels and hemodynamic data, is highlighted as crucial for patient stratification.

Conclusions:

  • Despite advances, CS mortality remains a significant challenge.
  • Improved, detailed assessment of shock severity holds promise for stratifying patients and potentially improving therapeutic efficacy and patient outcomes.
Abstract

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