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Published on: June 12, 2021
The changing face of cardiogenic shock: definitions, epidemiology, and severity assessment
Jacob C Jentzer1, David A Baran2
1Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
Insights
Cardiogenic shock (CS) definitions and severity assessment are evolving. Recent advances in evaluating CS severity may improve patient outcomes by enabling tailored therapies.
Area of Science:
- Cardiology
- Critical Care Medicine
Background:
- Cardiogenic shock (CS) is a critical condition, often stemming from myocardial infarction, with a long-recognized history.
- Despite decades of recognition, mortality rates for CS have remained largely unchanged.
Approach:
- This review synthesizes recent advancements in understanding CS, focusing on evolving definitions and epidemiological data.
- It details contemporary methods for assessing shock severity, including lactate measurement and invasive hemodynamic monitoring.
- The review examines the Society for Cardiac Angiography and Intervention (SCAI) consensus statement on the Classification of Cardiogenic Shock and its implications.
Key Points:
- Evolving definitions of CS are discussed, contrasting historical approaches with current concepts.
- Epidemiological trends of CS are presented.
- Granular assessment of shock severity, utilizing tools like lactate levels and hemodynamic data, is highlighted as crucial for patient stratification.
Conclusions:
- Despite advances, CS mortality remains a significant challenge.
- Improved, detailed assessment of shock severity holds promise for stratifying patients and potentially improving therapeutic efficacy and patient outcomes.
Purpose Of Review:
Cardiogenic shock (CS) has been recognized for >50 years, most commonly in the setting of myocardial infarction. This review covers recent advances in the definitions, epidemiology and severity assessment of cardiogenic shock.
Recent Findings:
In this review, the authors discuss the evolving definitions of cardiogenic shock, detailing the early approaches as well as more contemporary ideas. The epidemiology of CS is reviewed and then granular detail on the assessment of shock severity is provided including the role of lactate measurement and invasive hemodynamic assessment. The development of the Society for Cardiac Angiography and Intervention (SCAI) consensus statement on Classification of Cardiogenic Shock is reviewed by the principal authors. The revised SCAI Shock document is reviewed as well and the future directions for assessment of shock along with clinical applications are reviewed.
Summary:
Cardiogenic shock mortality has not changed in a significant way in many years. Recent advances such as more granular assessment of shock severity have the potential to improve outcomes by allowing research to separate the patient groups which may respond differently to various therapies.
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