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Updated: Jul 26, 2025

A Pre-Clinical Porcine Model of Orthotopic Heart Transplantation
Published on: April 27, 2019
Heart transplant in a Sars-CoV-2 positive recipient: Management protocol of the world's first case
Lorenzo Giovannico1, Antonio D'Errico Ramirez1, Domenico Parigino1
1Cardiac Surgery Unit, University of Bari Medical School, Piazza Giulio Cesare 11, Bari, Italy.
Abstract:
The advent of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in China at the end of 2019 has developed into a global outbreak, and COVID- 19 is an ongoing major public health issue. During the pandemic, transplant programs had to devise strategies to deal with the possibility of COVID-19-positive donors and recipients. We describe the case of a heart transplant recipient who tested positive with the SARS- CoV2 swab upon admission to our Unit of Cardiac Surgery when a suitable donor became available. Given his clinical status of end-stage heart failure and the absence of imaging and clinical signs suggestive of COVID-19, and his having been vaccinated with three doses, we decided to proceed with the transplant.
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