Phenanthroline-modified DNA three-way junction structures stabilized by interstrand 3:1 metal complexation

Yusuke Takezawa1, Daisuke Kanemaru1, Naofumi Kudo1

  • 1Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. takezawa@chem.s.u-tokyo.ac.jp.

Summary

This study shows that modifying DNA three-way junctions (3WJs) with phenanthroline ligands and nickel ions stabilizes the DNA structures. These metal-responsive DNA systems offer new possibilities for molecular construction.

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