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Meeting report: DMDG peptide and oligonucleotide ADME workshop 2022
Jesper Kammersgaard Christensen1, Inga Bjørnsdottir1, Anders Sonesson2
1Development ADME, Novo Nordisk A/S, Måløv, Denmark.
Abstract:
Challenges within peptide and oligonucleotide ADME (absorption, distribution, metabolism and elimination) and scientific ideas on how to solve them were presented and discussed at the DMDG (Drug Metabolism and Discussion Group) Peptide and Oligonucleotide ADME Workshop 2022 (2nd and 3rd of October 2022). This meeting report summarises the presentations and discussions from this workshop.The following topics were covered:Overview of the drug modality landscapeMetabolism & modellingAnalytical challengesDrug-drug interactions reports from industry working groupsRegulatory interactions.

