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Branched-chain keto acids inhibit mitochondrial pyruvate carrier and suppress gluconeogenesis in hepatocytes

Kiyoto Nishi1, Akira Yoshii2, Lauren Abell2

  • 1Mitochondria and Metabolism Center, Department of Anesthesiology and Pain Medicine, University of Washington, 850 Republican Street, Seattle, WA 98109, USA; Department of Pharmacology, Shiga University of Medical Science, Otsu, Shiga 520-2182, Japan.

Cell Reports
|June 13, 2023
PubMed

Keywords:
CP: Metabolismbranched-chain amino acidsbranched-chain keto acidsgluconeogenesismitochondrial pyruvate carrierpyruvate

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