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Bidirectional relationship between frailty and cognitive function among Chinese older adults
Siyue Han1, Tianjing Gao1, Guangju Mo1
1School of Public Health, Bengbu Medical College, Bengbu 233030, Anhui, China.
Frailty and cognitive function are bidirectionally linked in older adults. This relationship differs by sex, highlighting the need for tailored interventions to improve quality of life.
Area of Science:
- Gerontology
- Neuroscience
- Public Health
Background:
- Frailty and cognitive decline are prevalent aging-related conditions.
- Understanding their interplay is crucial for geriatric care.
- Sex-specific differences in these conditions are not well-established.
Purpose of the Study:
- To investigate the bidirectional relationship between frailty and cognitive function.
- To examine sex differences in this relationship among older adults.
Main Methods:
- Utilized data from the Chinese Longitudinal Healthy Longevity Survey (2008, 2014).
- Included 12,708 participants aged 65 years and older.
- Employed binary logistic regression and generalized estimating equation (GEE) models.
Main Results:
- A significant bidirectional link was found between frailty and cognitive impairment.
- Frailty predicted increased risk of cognitive impairment (OR=3.79).
- Cognitive impairment predicted increased risk of frailty (OR=3.68).
- Sex differences emerged: women with cognitive impairment were more prone to frailty.
Conclusions:
- Frailty and cognitive function exhibit a significant bidirectional relationship.
- This relationship is influenced by sex, with women showing distinct patterns.
- Sex-specific interventions are recommended for managing frailty and cognitive issues in older adults.
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