Related Experiment Video
Updated: Jul 26, 2025
Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
Published on: September 22, 2023
Household secondary attack rate in mild COVID-19
Ananthu Narayan1, Ushasi Saraswati2, Ishmeet Kaur3
1Department of Medicine, All India Institute of Medical Sciences, New Delhi, India.
The household secondary attack rate for COVID-19 was 41.85%, with children under 18 having lower infection odds. Effective quarantine significantly reduced transmission, highlighting households as high-risk units.
Area of Science:
- Epidemiology
- Infectious Disease Transmission
- Public Health
Background:
- The COVID-19 pandemic caused millions of deaths globally.
- Understanding household transmission is crucial for developing control strategies.
Purpose of the Study:
- To determine the secondary attack rate (SAR) of COVID-19 within households.
- To identify factors influencing SAR in households with mild COVID-19 cases.
Main Methods:
- An observational study involving 60 index COVID-19 cases and 184 household contacts.
- Data collected on patient outcomes post-discharge.
- Analysis of factors related to the index case and contacts affecting transmissibility.
Main Results:
- The overall household SAR was 41.85%.
- Children under 18 had significantly lower odds of secondary infection (OR=0.46).
- Effective quarantine measures drastically reduced transmissibility (OR=0.13).
- Symptomatic index cases and longer exposure periods increased infection risk.
- Healthcare worker index cases showed lower transmission rates.
Conclusions:
- Households represent a significant high-risk environment for COVID-19 transmission.
- Implementing proper quarantine for exposed individuals can mitigate household spread.
- Targeted interventions can reduce COVID-19 risk within family units.
More Related Videos
03:53Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
12:21A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness
Published on: September 28, 2022
Related Concept Videos
01:26Stages of Infection
01:29Pneumonia II: Pathophysiology
01:12Hazard Ratio
For example, in a clinical trial...
01:26Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
01:30Acute Pharyngitis
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
01:25Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...