Related Experiment Video For chronic obstructive pulmonary disease
Updated: Jul 26, 2025
Methodology for Sputum Induction and Laboratory Processing
Published on: December 17, 2017
Comparing chronic obstructive pulmonary disease and depressive disorder in terms of inflammation-related biomarkers
Elżbieta Małujło-Balcerska1, Kasper Sipowicz2, Tadeusz Pietras3,4
1Department of Pneumonology, Medical University of Lodz, Lodz, Poland.
Introduction:
Chronic obstructive pulmonary disease (COPD) is characterized by the presence of depressive symptoms.
Methods:
Cytokine and deiodinase iodothyronines (DIOs) levels were evaluated in COPD patients and patients diagnosed with depressive disorder and control individuals. using enzyme-linked immunosorbent assays.
Results:
Interleukin 1β (IL-1β), and tumor necrosis factor-α (TNF-α) levels were higher in COPD and depression patients than in control individuals. DIO2 were significantly lower in COPD and recurrent depressive disorder (rDD) patients than in controls.
Conclusions:
Changes in the levels of IL-1β, TNF-α and DIO2 in COPD patients may explain the presence of depression in COPD patients.
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