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Red Breast Syndrome and Acellular Dermal Matrix.
Allison Podsednik Gardner1, Aidee Nunez2, Mauricio De la Garza1,2
1From the University of Texas Rio Grande Valley School of Medicine, Edinburg, Tex.
Plastic and Reconstructive Surgery. Global Open
|June 14, 2023
Summary
Red breast syndrome (RBS), an inflammatory complication of acellular dermal matrix (ADM) in breast reconstruction, may resolve by switching to a different ADM brand. This suggests hypersensitivity could be a cause, offering a potential management strategy.
Area of Science:
- Plastic Surgery
- Biomaterials Science
Background:
- Acellular dermal matrix (ADM) is increasingly used in breast reconstruction for implant support.
- Complications such as infection and red breast syndrome (RBS) are associated with ADM use.
Observation:
- Red breast syndrome (RBS) presents as cutaneous erythema following ADM implantation.
- A case of RBS diagnosed in a patient undergoing breast reconstruction with ADM is described.
Findings:
- The patient's RBS resolved after surgical revision involving exchange for a different brand of dermal matrix.
- No recurrent erythema was observed over a 7-month follow-up period, maintaining reconstructive outcomes.
Implications:
- The findings suggest that patient hypersensitivity to specific ADMs may contribute to RBS.
- Revision with an alternate ADM brand could be a viable solution for managing ADM-associated RBS.
- Further research is needed to confirm ADM hypersensitivity as a cause of RBS and evaluate alternative ADM brands.
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