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Updated: Jul 26, 2025
Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
Published on: July 12, 2018
Prevalence and Natural History of Segmental Colitis Associated With Diverticulosis
Antonio Tursi1,2, Daniele Piovani3,4, Giovanni Brandimarte5
1Territorial Gastroenterology Service, ASL BAT, Andria, Barletta-Andria-Trani, Italy.
Introduction:
We assessed the prevalence and clinical outcomes of segmental colitis associated with diverticulosis (SCAD) in patients with newly diagnosed diverticulosis.
Methods:
A 3-year international, multicenter, prospective cohort study was conducted involving 2,215 patients.
Results:
SCAD diagnosis was posed in 44 patients (30 male patients; median age: 64.5 years; prevalence of 1.99%, 95% confidence interval, 1.45%-2.66%). Patients with SCAD types D and B showed worse symptoms, higher fecal calprotectin values, needed more steroids, and reached less likely complete remission.
Discussion:
Although SCAD generally had a benign outcome, types B and D were associated with more severe symptoms and worse clinical course.
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