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Updated: Jul 26, 2025

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
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Axially Chiral Cannabinoids: Design, Synthesis, and Cannabinoid Receptor Affinity

Sara E Kearney1, Anghelo J Gangano1, Daniel G Barrus2

  • 1Department of Chemistry, University of Florida, Gainesville, Florida 32611, United States.

Journal of the American Chemical Society
|June 14, 2023
PubMed
Summary

Researchers developed novel axially chiral cannabinols (axCBNs) and cannabidiols (axCBDs) by modifying the cannabinoid structure. These new compounds show promise for enhanced therapeutic properties and drug development targeting the endocannabinoid system.

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