Perthes' disease in rabbits and puppies

An effusion was simulated in the hip joints of rabbits and puppies known to be susceptible to Perthes' disease. The effusion was produced by the injection of glycol wax. The object of producing the effusion was to show that a transitory interruption of the venous flow was capable of producing changes that would subsequently manifest the pathologic changes and establish a Perthes-like disease.