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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Rothia Aeria Endocarditis Complicated with Multiple Systemic Embolisms.

Shigeaki Aoyagi1, Satoru Tobinaga1, Kumiko Wada1

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Summary
This summary is machine-generated.

Rothia aeria, a common oral bacterium, rarely causes severe infections. This case highlights its potential to cause infective endocarditis, particularly in immunocompromised individuals, leading to valve damage and systemic complications.

Keywords:
embolisminfective endocarditismitral valve repairrothia aeriastroke

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Area of Science:

  • Microbiology
  • Infectious Diseases
  • Cardiology

Background:

  • Rothia aeria is a commensal bacterium of the human oral flora.
  • Infections caused by Rothia aeria are rare, especially in healthy individuals.
  • The potential for oral bacteria to cause systemic infections warrants investigation.

Observation:

  • A 53-year-old man developed recurrent fever after licking a thumb wound.
  • Clinical presentation included a cardiac murmur, mitral valve damage, and systemic infarctions.
  • Blood cultures confirmed Rothia aeria as the causative agent.

Findings:

  • Rothia aeria was identified as the pathogen responsible for infective endocarditis.
  • The infection led to severe mitral regurgitation and multiple organ infarctions.
  • Successful treatment involved antibiotics and subsequent mitral valve repair.

Implications:

  • This case underscores the importance of considering rare pathogens in infective endocarditis.
  • The oral cavity can serve as a reservoir for bacteria causing serious systemic infections.
  • Prompt diagnosis and treatment are crucial for managing Rothia aeria endocarditis.