Association between inter-arm blood pressure difference and cardiovascular disease: result from baseline Fasa Adults...

Area of Science:

• Cardiology and Public Health

Background:

• Inter-arm blood pressure difference is a recognized indicator associated with cardiovascular mortality and morbidity.
• Previous research suggests a link between variations in blood pressure between arms and adverse cardiovascular outcomes.

Purpose of the Study:

• To investigate the association between inter-arm systolic and diastolic blood pressure differences and the risk of cardiovascular disease (CVD).

Main Methods:

• A cross-sectional study involving 10,126 participants aged 35-70 years from the Fasa Persian Adult Cohort.
• Blood pressure measurements were taken, and participants were categorized based on inter-arm blood pressure differences (e.g., <5, ≥5, ≥10, ≥15 mmHg).
• Descriptive statistics and logistic regression analysis were employed to evaluate the relationship between blood pressure differences and CVD risk.

Main Results:

• The prevalence of inter-arm systolic blood pressure difference (SBPD) ≥15 mmHg was 8.08%, and inter-arm diastolic blood pressure difference (DBPD) ≥15 mmHg was 2.61%.
• Logistic regression revealed that inter-arm SBPD ≥15 mmHg (OR=1.412) and inter-arm DBPD ≥10 mmHg (OR=1.518) were significantly associated with an increased risk of CVD.
• A strong positive relationship was observed between inter-arm blood pressure differences and CVD.

Conclusions:

• Inter-arm blood pressure differences, particularly significant variations in systolic and diastolic pressures, are positively associated with cardiovascular disease.
• Measuring inter-arm blood pressure difference can serve as a valuable marker for the prevention and diagnosis of CVD in clinical practice.