Follow-up studies in pattern VECP in demyelinating diseases in children

Demyelinating disease in children is known to be relatively rare. We report three cases defined as Devic's disease, acute disseminated encephalomyelitis, and multiple sclerosis. Follow-up studies of pattern appearance-disappearance visual evoked cortical potentials (VECPs) and pattern reversal steady state VECPs were performed. Results showed delays of appearance-disappearance VECPs that improved to shorter latencies with the improvement of visual acuity; however, recovery of VECPs was found to be behind the recovery of subjective vision. On the other hand, steady-state VECPs showed no normal waveforms even when vision recovered. Recovery of steady-state VECPs was found to be far behind that of transient VECPs and vision.