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The adhesion behavior of the retina
Chenxi Zhang1, Yunfei Lan1, Hongmei Guo2
1College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, 030024, China.
Experimental Eye Research
|June 15, 2023
Summary
This study investigated retinal adhesion using pull-off and peeling tests on porcine eyes. Findings provide crucial biomechanical data for understanding retinal detachment (RD) and improving surgical repair strategies.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Materials Science
Background:
- Rhegmatogenous retinal detachment (RRD) treatment is linked to retinal adhesion.
- Understanding retinal adhesion is key for treating RRD and related diseases.
Purpose of the Study:
- To systematically study the adhesion behavior of the intact retina.
- To provide theoretical guidance for RRD treatment and research.
Main Methods:
- Pull-off test with modified JKR theory for vitreoretinal interface adhesion.
- Peeling test for chorioretinal interface adhesion.
- Finite element method (FEM) simulation for adhesion analysis.
Main Results:
- Pull-off force increased with punch radius (0.5-4 mm) for the vitreoretinal interface.
- Significant scale effect observed in retinal work of adhesion.
- Chorioretinal interface showed maximum peeling strength of 13 mN/mm and stable strength of 11 mN/mm.
Conclusions:
- Experimental and FEM results for pull-off force showed good agreement.
- Peeling test provided key biomechanical data for the retina-choroid adhesion.
- Combined experimental approach offers comprehensive data for retinal disease modeling and surgical design.
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