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Updated: Jul 26, 2025

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache
Published on: July 29, 2021
Alexandra M J V Schyns-van den Berg1, Anil Gupta2
1Department of Anesthesiology, Albert Schweitzer Hospital, Dordrecht, the Netherlands; Department of Anesthesiology, Leiden University Medical Centre, Leiden, the Netherlands.
Postdural puncture headache (PDPH) can occur after accidental or intended dural punctures, causing significant disability. While epidural blood patch is effective, this review covers PDPH pathophysiology, diagnosis, prevention, and future treatments.
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