Related Experiment Video
Updated: Aug 9, 2026
18:40
Combined In vivo Optical and µCT Imaging to Monitor Infection, Inflammation, and Bone Anatomy in an Orthopaedic Implant Infection in Mice
Published on: October 16, 2014
Pathological features of multiple bone infection in the foal
The Veterinary Record
|November 25, 1978
Summary
Multiple bone infections in foals primarily affect the growth plate, causing significant bone and cartilage destruction. This study details the pathological features and discusses the pathogenesis of foal bone infections.
Area of Science:
- Veterinary Pathology
- Equine Medicine
- Skeletal Biology
Background:
- Bone infections in foals can lead to severe lameness and developmental issues.
- Understanding the specific sites and mechanisms of infection is crucial for effective treatment.
- Growth plate (physis) is a critical area for bone elongation and is susceptible to injury and infection.
Observation:
- Two foals presented with multiple bone infections.
- Lesions were localized to the metaphyseal and epiphyseal regions of the growth plate.
- Gross examination revealed bone destruction, while histological analysis showed extensive inflammatory cell infiltration.
Findings:
- Significant destruction of bone and, in some cases, growth plate cartilage was observed.
- Inflammatory cell infiltration was a prominent feature in affected areas.
- The pathological findings provide insights into the progression of bone infection in young horses.
Implications:
- The study highlights the growth plate as a primary target for bone infections in foals.
- Understanding these pathological features aids in diagnosing and managing equine osteomyelitis.
- Further research into the pathogenesis can inform preventative strategies for foal bone diseases.
