Illustrations of interactions needed when investigating sleep using a type of AM-PM PM-AM design

Sleep has long been thought of and promoted to be beneficial for memory. Some claims that sleep aids memory have been made in the absence of a critical interaction. This condition is necessary when using a commonly-used experimental design (a type of AM-PM PM-AM design). We propose that a sleep effect exists only if there is an interaction between groups (experimental and time-of-day controls) and the time of test or study (morning and evening). We show different patterns of results that would and would not support a sleep effect with empirical and model-generated data from recognition memory experiments and hypothetical data. While we use these data to make our point, our suggestions apply to any memory and non-memory-related investigation (e.g., emotional memory, false memory susceptibility, language learning, problem-solving). Testing for and finding the proper interaction will add to the evidence that sleep boosts performance.